Some thoughts on interpreting statistics re. the new multivitamins-fight-cancer JAMA study.

A new vitamin study just published in the Journal of the American Medical Association (full text freely available here ) is front-page news today. The finding: In this large prevention trial of male physicians, daily multivitamin supplementation modestly but significantly reduced the risk of total cancer. This is a significant finding, because the trial was big (14,641 male physicians over the age of 50), long (average follow-up time of 11 years), and well-conducted (randomized, double-blinded, and placebo-controlled). It's also significant because it runs counter to the majority of recent findings about the health benefits of vitamin pills. I've been highly critical of the weak evidence for vitamin use in the past, so a well-designed study like this is a signal that I might need to change my tune. The reduction in overall cancer risk was 8% -- relatively modest, but certa...

Full article: http://sweatscience.runnersworld.com/2012/10/multivitamin...

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